Opening Credits: Blackboard joke: I will not sleep through my education. Couch gag: The family runs in and sits on the couch; the floor beneath the couch gives way and the Simpson family falls down into the hole.
Act One: Outside the nuclear power plant, Mayor Quimby stands at a podium in front of a crowd and dedicates the new power plant threat warning sign. When Mayor Quimby hands the podium over to Mr. Burns, everyone looks around and Smithers senses something is wrong; Mr. Burns is nowhere to be found. At Mr. Burns' mansion, Smithers finds Mr. Burns, who has collapsed on his bedroom floor. Dr Hibbert is rushed over right away for an emergency house visit, and he diagnoses Mr. Burns with hypohemia, or a lack of blood. He informs Smithers that Mr. Burns needs a blood transfusion; Smithers rips his shirt off, right there on the spot, ordering Dr. Hibbert to, "Just leave me enough to get home." Dr Hibbert chuckles and explains to Smithers that Mr. Burns is a double-O-negative blood type, which is extremely rare.
At the power pant the next day, Smithers makes an announcement over the P.A. system, informing all the workers that Mr. Burns needs double-O-negative blood, and he urges anyone that can donate blood, to do so. Carl, Lenny and Homer listen to the announcement together and Homer senses an opportunity to make some money off of Mr. Burns. At home in the family room, Marge reads a book, while Lisa is busy showing flashcards of animals to Maggie. Homer arrives home and rushes in the front door asking Marge what his blood type is. Marge tells Homer that he is A-positive, and Homer is bummed that he can't donate his blood. But, when Homer explains the situation with Mr. Burns, Marge tells him that Bart has double-O-negative blood. A happy Homer rushes over to Bart and tells him that he has a date with a needle. Bart, however, doesn't like the idea of donating blood.
That night, Homer tucks Bart into bed and tells him the "legend" of Hercules and the Lion. Homer explains that when Hercules pulled a thorn out of the Lion's foot, Hercules was showered with riches. Homer likens his story to the situation that Bart is in, and explains that if he donates his blood, Mr. Burns will reward them with lots of money. Bart reluctantly agrees to donate. The next day at work, Homer brings Bart to the bloodmobile to donate his blood. Otto, who also works as a bloodletting tech, takes some of Bart's blood and quickly rushes it to the hospital. A frail Mr. Burns lies in his bed and struggles, as he attempts to dictate his epitaph to Smithers. As soon as Bart's blood is hooked up to an IV and drained into Mr. Burns' veins, he becomes instantly invigorated and energetic. The next day at the power plant, a jolly Mr. Burns, with a new lease on life, struts around and cheerfully converses with his employees. Homer notices that the vibrant Mr. Burns has recovered, and celebrates quietly, telling himself he has hit the jackpot.
After a round of racquetball, Mr. Burns retires to his office and inquires to Smithers about who donated the blood. Smithers informs Mr. Burns that it was Bart Simpson, the son of an employee. Mr. Burns reclines in his chair and tells Smithers that the Simpson family will be receiving something very nice in the mail.
The next day at the Simpson home, Homer hastily searches through his mail and is excited to find an envelope addressed from Mr. Burns. Homer quickly rushes everyone outside to open the envelope, so the neighbors can see how much money the Simpsons are going to receive. However, Homer is shocked when he opens the envelope to reveal only a thank-you card. In the kitchen, Homer is furious about not receiving any money and Marge tries to calm him down. But Homer won't listen and he orders Bart to take down a letter. Bart writes the letter as Homer dictates a sarcastic and angry message full of insults to Mr. Burns. Homer promptly rushes out to a mailbox to mail the letter, while Marge follows behind, pleading with him to change his mind. Just before Homer drops the letter in the mailbox, Marge's voice of reason sinks in and he promises to sleep on it, before making a decision to mail the letter. The next morning at the breakfast table, a cheerful Homer, thanks Marge for stopping him the night before, as he realizes that mailing the letter would have been a mistake. Homer wonders aloud where the letter is and meanwhile, in town, Bart whistles as he walks down the street and deposits Homer's letter in a mailbox.
Act Two: At home in the kitchen, a suddenly panicked Homer searches frantically for his letter. A whistling Bart strolls through the kitchen and Homer stops him and desperately asks him where the letter is. Bart explains that the letter contained things that needed to be said, and he knew Homer would change his mind in the morning, so he went ahead and mailed the letter for him. An angry Homer promptly begins choking Bart. Marge intervenes, and tells Homer it was his fault for encouraging Bart to write the letter the night before. Homer quickly shifts gears and begins to think of a way to prevent Mr. Burns from receiving the letter.
Homer takes Bart back to the mail box; Homer tries reaching in the mailbox to retrieve the letter, he tries pummeling the mailbox into submission, and finally he decides to grab a nearby hose and flood the mail box, thereby ruining the letter. Bart tries to be the voice of reason, and reminds Homer that other people's mail is also in the mailbox, but Homer won't listen. However, just before Homer can begin flooding the mail, the mail carrier catches him in the act. Homer yelps and he and Bart take off running.
At Mr. Burns' mansion, Mr. Burns and Smithers sit down and have a meeting with a ghostwriter, who Mr. Burns would like to hire to write a book about his eventful life and bout with hypohemia. The ghostwriter starts off by asking Mr. Burns if he has slept with anyone famous; Mr. Burns is instantly offended and fires the ghostwriter, claiming that he will write the book himself. Meanwhile, at the Post Office, Homer unsuccessfully tries to impersonate Mr. Burns, in an attempt to recover his letter. Back at home, a worried Homer lies on the couch, while Lisa shows some more flash cards to Maggie.
On Monday morning at the power plant, Homer cautiously stands outside of Mr. Burns' office and prepares to infiltrate the office and steal his letter, before Mr. Burns arrives to read his mail. However, Mr. Burns is already in his office, working on his book. Homer enters the office and sifts through Mr. Burns' mail, as Mr. Burns approaches from behind, returning back to his desk with a letter opener. A startled Homer stops what he is doing, and when Mr. Burns asks for his name, Homer tells him. A cheery Mr. Burns spots the letter from Homer on the top of the pile of mail and opens it in front of Homer. Homer tries to quietly back away, as Mr. Burns reads his letter out loud. The old man's cheery demeanor quickly turns sour though, as he reads through Homer's letter. Mr. Burns promptly calls for Joey, one of his security guards, to escort Homer off the property. Mr. Burns watches from his perch in his office, as Homer is escorted out to the back gate of the power plant. Mr. Burns vows to exact revenge from Homer and also to, "Crush him like an ant."
Act Three: Smithers counsels an enraged Mr. Burns, who signs Homer's pink slip. After signing the pink slip, Mr. Burns tells Smithers that something doesn't feel right, so he orders Smithers to have Homer beaten to a pulp as well. Smithers nervously hesitates for a moment and then accepts Mr. Burns order.
Later, at the Simpson home, Homer frets over the future of his family after losing his job. Meanwhile, Smithers is having trouble ordering Joey to beat up Homer. Joey asks what Homer did in the first place to deserve the beating and Smithers breaks down crying and tells Joey that Homer saved Mr. Burns' life. Later, Mr. Burns works on writing his book in his study, when Smithers pokes his head in the door. Mr. Burns asks how Homer's beating went and Smithers confesses; he explains that he called the beating off and that he just couldn't have Homer beaten, after saving Mr. Burns' life. Mr. Burns comes to his senses and realizes the error of his ways, and he forgives Smithers. Meanwhile, at Moe's a depressed Homer drinks a beer alone, while Bart plays a prank call on Moe.
The next day at the mall, Smithers accompanies an excited Mr. Burns, who is searching for the perfect gift for the Simpson family. After searching several stores, Mr. Burns spots the Simpsons' perfect present through the front window of a store called "Plunderer Pete's," a store where exotic items from all over the world are sold. Smithers notes that the item costs $32,000, but Mr. Burns doesn't seem to care. Later at the Simpson home, as a depressed Homer sits on the couch, Mr. Burns pulls into the driveway with some moving men, who are unloading a giant crate off a truck. The moving men set the crate down in the Simpson living room and Mr. Burns explains to a bewildered Homer that this is a present for the blood transfusion. Mr. Burns hands Bart a crowbar and Bart pries open the giant crate to reveal a large Olmec Indian head. The Simpsons are a bit miffed at the giant head, as a proud Mr. Burns explains its historic importance.
Later, the Simpson family eats microwave TV dinners on the couch and stares at the giant head. Marge tries to come up with a moral to the story, but when she can't, the family simply agrees that at the very least the past few days had been very memorable.
End Credits: The normal Simpons theme plays as the credits roll over a black background.
Run Time: 22:56