The opening title sequence is seen as more like a video game (including graphics), that parodies Minecraft. The title is seen as Simcraft (Parodies are easy!). The sequence simply shows the family walking through various Springfield sites before they all enter through the garage. They calmly sit on the couch, then Moe (seen as a green mechanical bar machine mirroring creepers from that game) asks how they're doing before he explodes and blows the house apart, creating a big hole to the basement and showing various furniture in other parts of the home.
The brand name of the bottle of cologne that Marge looks at in the bathroom is Papa Don't Reek. The name is a take on the song "Pappa Don't Preach" by Madonna.
The song is featured on her 1986 album True Blue.