The episode apparently conflates all tropical peoples, as circumcision does not occur in the Amazon. Or among any indigenous peoples in the Western Hemisphere.
Ms. Quymn: Why, was I too fast for you, Horace?
Col. Gentleman: Never let a woman drive your Aston, Jonesie. This one handles a stick like it's got herpes.
Ms. Quymn: Well, who knows, with all the strange garages you park it in.
Brock: So no more teaching chimps to box, huh? By the way, thanks for that new personal low.
Dr. Venture: The only wet blankets I'm interested in are the ones…
Brock: All right, I know where this is going.
Dr. Venture: You know, when we're sweating…
Dr. Venture: Rolling around…
Dr. Venture: When we're having..
Brock: Okay, Doc, I get it.
Dr. Venture: All right. Just making sure we're on the same page here. (pause) Sex.
Ginny: Stay close. Natives are suspicious of outsiders ever since that Ikea opened up down the river.
Tara: The logging company that supplies the lumber for their Billy bookcase has been trying to force them off their ancestral lands.
Tara: He says it tore the head off their mightiest warrior. He says it was as if someone shook up a six-foot can of… blood soda… and somebody popped the top.
Hank: Frith help us. Play it cool, Dean-O. You step to them with that line and they're going to think you're some crazy obsessed weirdo stalker who, like, draws pictures of them in your notebook.
Dean: They're for the Venture Home News Pictures increase circulation.
Hank: Yeah, and they think you like, talk to the pictures and then, and then, you cut out the lips and the eyes with like a razor bade and then you write dirty words on them with your own poop, and then you rub them on your chest.
Dean: What…where did…/?
Hank: Man, what's your hurry?
Dean: What's your slow-ey? You've gone soft on me, Henry Allen So-Called Venture! You used to be all "Go, Team Venture!" But now you're all… "Go, Team… Boobies!"
Dr. Venture: Whoa! Think I've found my cure for impotence after all. Now, if I could just find a way to bottle that ass, I'd be a multimillionaire.
Dean: Dr. Quymn is the were-o-dile!
Dr. Venture: She's.. oh my God, I almost *bleep* a were-o-dile!
Dean: The mystery is afoot.
This is a reference to Sir Arthur Conan Doyle's famous mystery character, Sherlock Holmes, who would say, "The game's afoot" when referring to a mystery.
Hank: Bang, Clyde!
The boxing orangutan is a reference to the 1978 film Every Which Way but Loose and its 1980 sequel Any Which Way You Can. Both films starred Clint Eastwood as a trucker who travles across the American West with his pet orangutan, named Clyde, getting into fights and looking for his lost love.
Ginny: Hard rain's gonna fall. hard rain.
Referencing Bob Dylan's song A Hard Rain's a-Gonna Fall (1962), from his album The Freewheelin' Bob Dylan. the lyrics Ginny recites here are paraphrased.
Dean: The power of Christ compels you!
Referencing the line best known from the movie The Exorcist (1973), based on the novel by William Peter Blatty. Fathers Merrin and Karras recite it repeatedly to drive the demon from the possessed Regan (Linda Blair).
The title of the episode is a play on the TV series Dr. Quinn, Medicine Woman, which ran on CBS from 1993 to 1998 and starred Jane Seymour as a female doctor in the 1860's American frontier. However, the setting of this episode and the attempts by Dr. Quymn to cure cancer has more in common with the 1992 film Medicine Man starring Sean Connery.
Nancy and Drew
Referencing the female teenage detective Nancy Drew. Nancy Drew was created by Mildred Wirt Benson under the pen name "Carolyn Keene." The character is probably known best under her TV incarnation in The Hardy Boys/Nancy Drew Mysteries from 1977, where she was portrayed by Pamela Sue Martin.