Ryan Giggs made his 800th appearance with Manchester United in this match.
Real Madrid's 4-0 defeat by Liverpool, was their biggest one in Champions League.
Liverpool's Steven Gerrard reached 100 European matches during this matchday.
Panathinaikos win against Inter, was their first away win ever, against an Italian team in any European competition.
Anorthosis became the first team from Cyprus to enter the Group Stage of Champions League.