Now away from Neverland Ranch, Buddy and Woof go to Malibu, only to be chased out by Dogcatcher. They end up with Jennifer Aniston, who's a big hit on mespace.com. So Buddy tries to reach Jeffy with a little help from the internet.
Buddy and Woof take a trip to the dog park where Kourtney Love gives Buddy worms. Soon after they meet Whitney Houston and Bobby Brown who mistakes them for their kids. With Buddy slowly dying he abandons all hope of trying to get home to Jeffy.
In the pilot episode, our canine heroes meet in the dog pound. From there, they get the celebrity treatment from Lindsay Lohan and friends followed by a stay with Angelina Jolie. They soon find out that her son Maddox can be quite the handful.