Another rare appearance by a living animal happens in this episode. The reindeer joins Lassie and two snakes who were props for a pair of belly dancers.
Drew: I know you don't see any Christmas decorations around here. That's because we took the money that ABC gave us for Christmas decorations and we drank it.
(Scenes from a Hat)
Drew: 'Celebrities who shouldn't release rap records.'
(Colin comes to the stage and gets buzzed)
Drew: It said, 'Celebrities.'
Colin: I'm sorry, I thought you said, 'Studs.'
(About the small reindeer poop that Donner left.)
Wayne: Now that's a Christmas present for ya.
Ryan: I expected something bigger.
(Questions with Wigs)
Colin: (in a girl wig) Somebody call for a Christmas "Angel?" (strikes a "Charlie's Angels" pose)
Brad: Why do you look more like Bosley?
Colin: Don't you know I'm undercover?
Brad: Shouldn't you stay there?
Drew: Welcome to a very special Christmas episode of Whose Line Is It Anyway?! (laughter) As you can tell by our "expensive decorations," it's our Christmas episode. Yup, that's how our Christmas special goes. You know, a lot of Christmas specials have, you know, fake snow, carols, warm-hearted stuff. Not us. We just throw the word "Christmas" into stuff.
This episode came from the same taping as Show No. 506, featuring Joanie Laurer, aka Chyna.
When Questions With Wigs starts, Ryan can be seen wearing a Mr. Heatmeister wig of flaming hair. But, Ryan, nor any of the other contestants, ever actually show up in the game itself wearing this wig.
In one episode, the name "Stephen Hawking" is bleeped, but here when Brad makes fun of him, it is uncensored.
Due to all the holiday-themed programming, there was only one new episode in December 2005.