James Burrows directed every episode of the series, including the pilot and the series finale.
Karen made a joke about knowing Marlo Thomas, which is a running joke which began in the season 1 episode, "The Truth About Will And Dogs".
Allusions to previous episodes: The scene at the end with Will and Grace on the phone is intentionally reminiscent of the opening scene of the pilot, including a reference to ER and George Clooney.
The final scene is held at what appears to be the same bar in "The Pilot (Love and Marriage)" where everyone thought Will & Grace had just been married and got them to kiss each other.
Jack and Karen touch tummies just like they did when they first met in the season 1 episode "A New Lease On Life".
Eric McCormack (Will), Sean Hayes (Jack), and Megan Mullally (Karen) appeared in every episode of Will & Grace. Debra Messing (Grace) was absent from a few season six episodes when she was pregnant.
The final song played at the end is "You're My Best Friend" by Queen.
This episode was Entertainment Weekly's Pick of the Week.
Warren: I'm going over to Sandoval's.
Steve Sandoval is a producer for the show.
Hospital page: Dr. Kohan... extension 456... Dr. Kohan extension 456.
David Kohan is one of the show's creators.
(In the final scene, in the same bar as in the first episode)
Grace: On three.
Jack: One. Two--
Jack: Uh, why'd you stop me? I was gonna say three, four, slam it whore.
Grace: (to Will) C'mon, the glass is clean.
Will: No, I was gonna propose a toast--to family. Family that loves you, and accepts you for exactly who you are.
Karen: Too real.
Will: Ya know what's funny? We haven't changed a bit.
Grace: It's kinda nice, isn't it?
Grace: (to her pregnant belly) Would you like to hear a song?
Will: Yeah, Grace--could you do me a favor? Could you not sing to the baby anymore?
Grace: Why not? Music makes them smarter.
Will: Okay, well if you're gonna sing, have a glass of wine 'cause he--he's gonna want to be drunk for this.
Karen: I think I feel a song coming on.
Jack: Then a song, we shall have.
(They walk to the piano)
Jack: And might I say, your knockers are looking particularly full tonight.
Karen: And might I say, you have the balls of a thirty-year-old.
Karen: Why don't you go pick out a book. Maybe I can teach ya a few words of English tonight, huh? Rosario: Suck it, b*tch.
Karen: Would you look at us? Will's mean, Grace is flat-chested... Jackie's pretending like he's following this... And I'm high from something I found under the sink in your bathroom. Ah... The gang is back.
Grace: Lila was so skinny her whole first year.
Will: What'd you feed her?
Grace: The boob.
Will: Portion control. Good idea!
Beverley: You may or may not know this, but my business associate Benji and I have come to a parting of the ways.
Jack: And I thought you two would last for ever. You were definitely the most stable-in the closet-short-tall-black-white-young-old-disgusting-hot-couple I know.
Karen: Why Beverley Leslie, what are you doing later tonight honey? I'm having a few friends over for a game of Monopoly, and I'm missing one of the pieces.
Karen (in a baby voice): Oh, are we hungry? Does somebody need something to eat?
Rosario: I just broke my ankle, you douche bag. I'm not an infant.
Karen: Hey honey, what's up?
Jack: Oh, nothing. I'm not desperately trying to get hobbit germs off my kissing hand, if that's what you're thinking.
Jack: Karen, you accidentally hit the stop button with your shoe.
Karen: Jack has told his hilarious story and you're out of vodka.
Will: There's a bottle right there.
Karen:(Drinks the bottle of vodka) Nope, empty.
Jack: He's clearly Will's child. Fat, bald, and clinging to Vince like it's the only man who'll ever love him.
Beverly: Karen Walker, in the flesh. Whose flesh is unclear.
Will: Wow. We just fell for the dumbest version of Parent Trap ever.
Jack: (to Karen) What's the story, drunken whorey?
Vince: He's looking more like you everyday.
Will: Really? I don't know. Sometimes I see me, and sometimes I just see the sad girl who sold her eggs for rent money.
Will: The relationship you have with the chicken is truly remarkable. I can't wait for the day when someone inhales my leg and thigh like that.
Grace: I don't know what to tell you, man. Jews and chicken... it's real and it's deep.
Will: You married Kevin Bacon?
Jack: Stalked him all the way to the altar.
Jack: (humming the Wedding March) Step together step. Kick ball change. Pas de bourrée and I'm married.
Will: Where did you get married, on the sun?
Jack: That's funny, do you hear screaming? Oh, no, that's just the buttons on your shirt.
Grace: Have another drink.
Will: Have another doughnut.
Will: You're not going to wear that, are you?
Grace: Why, what's the problem with it? All the kids are wearing it.
Will: Yeah, and from what I can see, a bunch of them are in there with you.
Karen: Honey, ya know what I love about our plan to pay off a nurse to direct Will and Grace to the hospital room of a total stranger in a full body cast whose face is covered in bandages, each one of them thinking it's one of us in that bed with our bones broken?
Karen: The simplicity.
Grace: Alright, let's play the game with Vampira and the Bride of Franken-Dyke.
Grace: You look good.
Will: Thank you. You don't look anything like your mother.
Grace: Oh thank you!
Karen: Do you find them exhausting?
Jack: I always have.
Grace: Do you find them exhausting?
Will: Always have.
Jack: Well, not everything's the same. Karen here has lost her...
Karen: (cuts Jack off) Virginity!
Grace: Screw you!
Will: You wish.
Grace: You couldn't
Will: Yeah, not because I'm gay, just because you're hideous.
Will: (Grace stares at the apartment) You don't like the changes we made?
Grace: No it's just... I don't live here anymore.
Jack: (to Beverly Leslie) I'm sure you have places to be....A magic ring to protect....
Regarding the finale, Mutchnick stated, "We wrote about what you want to have happen with people you love. All the things that matter in life, they end up having".
The Finale was filmed over a period of three days-- 4/10, 4/11 and 4/13 of 2006. This was due to the fact that they had to use over 10 sets and it would have taken much too long to do it all in one day.
This is the first episode written by show creators Max Mutchnick and David Kohan since the season 4 episode, "A Buncha White Chicks Sittin' Around Talkin'".
This was a one-hour series finale, and aired in a special 9 p.m. timeslot following a one-hour retrospective titled "Will & Grace: Say Goodnight Gracie."
Vince: Look at this...Terri Hatcher buys her own produce. That's normal.
Even though Vince is reading a People magazine, the feature he's reading comes from The Star called Normal/Not Normal.
Jack: I'm sure you have places to go, a magic ring to protect.
A jab at Beverly Leslie's size, referring to Frodo from Lord of the Rings always having to protect a magic ring.
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