After drinking all of those bottles, Shaggler poops in his diaper. But when they go into the armory, they smell his full diaper,which he isn't wearing anymore. But when it shows Shaggler standing next to them, he's wearing a new diaper.
New Move Debut: Trans-foo-shrink-lify is a move used by Yin inside Master Yo's cruiser ship to shrink the ship with Yin and Yang inside until they're tiny enough to fit inside Master Yo's body.
(Yin and Yang emerge from Yo's ear)
Master Yo: You were in my ears?! I only clean those things once every 100 years! That's totally gross!
Yin: (yells) Do NOT talk to ME about gross EVER AGAIN!!!
Master Yo: (covers his ears) Heck of a time for me to be able to hear again!
(The elephant security robot attacks Yin and Yang)
Yin: I hope your trunk is packed, cause you're going dow--oh, great! Now I'm doing it to!
Kraggler as a Baby: (to Yin and Yang You two are the worst baby-sitters in history!!!!
Yang: But I let you play with my face.
Yin: Go inside him??
Yang: It could be worse.
Yang: (thinks) Uh, I don't really have an answer for that.
Yang: We're in (Yo's) nose? This is the grossest thing ever. Awesome!
This is the first time we see Kraggler as a baby, a kid, and a teenager.
This episode is only the latest parody of the 1964 movie THE FANTASTIC VOYAGE, where a team of surgeons go inside their patient's body to destroy a fatal tumor. It could also be a parody of "Journey to the Center of the Earth."
The episode title segment Voyage to the Center of the Yo is a reference to a famous 19th century Jules Verne book called Journey to the Center of the Earth.