For the record, it will be coupled with Scrubs, so it's not like ABC is just going to let this fly off solo into the graveyard. It's odds of coming back are pretty slim though because
1) Scrubs isn't a massive hit in the first place and is just going through the motions before it ends in May.
2) A lot of Scrubs viewers don't really check out the offerings that air afterward. Case in point, 30 Rock. They might not even give this a chance.
3) Scrubs leaving in May means The Goode Family would have to put up some pretty solid numbers to return in the fall of '09, considering that ABC would need another show to pair it with.